11 years after he first topped the bill at the festivals, the iconic rap artist returns next summer for what will be his only UK festival appearance in 2013.
Eminem joins already announced acts including Deftones, Alt-J, Sub Focus and Boy Better Know fr. Wiley, JME and Skepta.
Last week the festival announced that two more stages would be added for 2013, to accommodate even more acts across the two days.
More acts will be revealed in the coming weeks.
Reading and Leeds Festival takes place across the weekend of 23-25 August in 2013.